Product Usage: This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals. It is not approved for human or animal consumption. Misuse, misbranding, or mislabeling as a drug, food, or cosmetic is strictly prohibited. All information provided is for educational purposes only.
Kisspeptin-10
£49.99
In stock
Kisspeptin-10 is a decapeptide fragment of the kisspeptin protein, a crucial regulator of mammalian reproductive function. This peptide has gained significant attention in the scientific community due to its pivotal role in the hypothalamic-pituitary-gonadal (HPG) axis, puberty onset, and fertility. Kisspeptin-10 acts as a potent stimulator of gonadotropin-releasing hormone (GnRH) secretion, making it a promising target for the treatment of reproductive disorders and hormone-dependent cancers. Requires reconstitution before use.
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Size:
5 mg
Ships tomorrow morning if ordered by 2PM UTC
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Kisspeptin-10
£49.99
In stock
Buy 3+ for £50 each and save 5%
Buy 5+ for £50 each and save 8%
Buy 10+ for £50 each and save 10%
Loading stock...
Size:
5 mg
Ships tomorrow morning if ordered by 2PM UTC
Free international delivery within 1-3 business days on orders over £250, with a tracking number provided.
Third party tested
FREE Bacteriostatic Water
For every £75 you spend, get 1 FREE bottle of Bacteriostatic Water to reconstitute your peptides.
Kisspeptin-10 is a decapeptide fragment of the kisspeptin protein, a crucial regulator of mammalian reproductive function. This peptide has gained significant attention in the scientific community due to its pivotal role in the hypothalamic-pituitary-gonadal (HPG) axis, puberty onset, and fertility. Kisspeptin-10 acts as a potent stimulator of gonadotropin-releasing hormone (GnRH) secretion, making it a promising target for the treatment of reproductive disorders and hormone-dependent cancers. Requires reconstitution before use.
Product Usage: This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals. It is not approved for human or animal consumption. Misuse, misbranding, or mislabeling as a drug, food, or cosmetic is strictly prohibited. All information provided is for educational purposes only.
Characteristics
Molecular Formula
C225H348N60O68
CAS Number
2023788-19-2
Molar Mass
5047.61g/mol
Amino Acid
Sequence
His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Synonyms
LY3298176
Solubility
Water-soluble |
Organoleptic Profile
White to off-white powder
Composition
Lyophilized powder - requires reconstitution
How does Kisspeptin-10 work?
Kisspeptin-10 exerts its effects primarily through binding to the G protein-coupled receptor 54 (GPR54), also known as KISS1R. This interaction triggers a signaling cascade that leads to the release of GnRH from hypothalamic neurons. The released GnRH then stimulates the anterior pituitary gland to secrete luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn regulate gonadal function and steroidogenesis.
Research
Puberty Onset: Research has shown that kisspeptin-10 plays a critical role in the initiation of puberty. Studies in various animal models have demonstrated that the activation of the kisspeptin system is essential for the onset of puberty and the development of secondary sexual characteristics.
Reproductive Function: Kisspeptin-10 is integral to the regulation of the reproductive axis in both males and females. It modulates the pulsatile release of GnRH, which is crucial for normal gonadal function and fertility.
Metabolic Regulation: Emerging evidence suggests that kisspeptin-10 may also be involved in metabolic regulation, potentially linking reproductive function with energy homeostasis.
Reproductive Disorders: Given its role in the HPG axis, kisspeptin-10 has been investigated as a potential treatment for various reproductive disorders, including hypogonadotropic hypogonadism and polycystic ovary syndrome (PCOS).
Infertility: Clinical trials have explored the use of kisspeptin-10 in assisted reproductive technologies, particularly for in vitro fertilization (IVF) protocols, as an alternative to traditional hormonal stimulation methods.
Hormone-Dependent Cancers: Some studies have suggested that kisspeptin-10 may have anti-metastatic properties in certain hormone-dependent cancers, such as breast and prostate cancer, although more research is needed in this area.
Side Effects
While kisspeptin-10 is generally well-tolerated, some potential side effects have been reported in animal studies and mammalian clinical trials. These include:
Transient hot flushes
Mild headache
Nausea
Fatigue
Injection site reactions (e.g., redness, swelling, or pain)
Summary
While kisspeptin-10 shows promise in various therapeutic applications, several challenges remain. These include optimizing delivery methods, understanding potential long-term effects, and elucidating its interactions with other neuroendocrine systems. Ongoing research aims to address these challenges and further explore the therapeutic potential of kisspeptin-10 in reproductive medicine and beyond.
In conclusion, kisspeptin-10 represents a significant area of interest in reproductive endocrinology and neuroendocrinology. Its central role in the HPG axis and potential therapeutic applications make it a valuable target for continued scientific investigation and clinical research.
Characteristics
Molecular Formula
C225H348N60O68
CAS Number
2023788-19-2
Molar Mass
5047.61g/mol
Amino Acid
Sequence
His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Synonyms
LY3298176
Solubility
Water-soluble |
Organoleptic Profile
White to off-white powder
Composition
Lyophilized powder - requires reconstitution
How does Kisspeptin-10 work?
Kisspeptin-10 exerts its effects primarily through binding to the G protein-coupled receptor 54 (GPR54), also known as KISS1R. This interaction triggers a signaling cascade that leads to the release of GnRH from hypothalamic neurons. The released GnRH then stimulates the anterior pituitary gland to secrete luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn regulate gonadal function and steroidogenesis.
Research
Puberty Onset: Research has shown that kisspeptin-10 plays a critical role in the initiation of puberty. Studies in various animal models have demonstrated that the activation of the kisspeptin system is essential for the onset of puberty and the development of secondary sexual characteristics.
Reproductive Function: Kisspeptin-10 is integral to the regulation of the reproductive axis in both males and females. It modulates the pulsatile release of GnRH, which is crucial for normal gonadal function and fertility.
Metabolic Regulation: Emerging evidence suggests that kisspeptin-10 may also be involved in metabolic regulation, potentially linking reproductive function with energy homeostasis.
Reproductive Disorders: Given its role in the HPG axis, kisspeptin-10 has been investigated as a potential treatment for various reproductive disorders, including hypogonadotropic hypogonadism and polycystic ovary syndrome (PCOS).
Infertility: Clinical trials have explored the use of kisspeptin-10 in assisted reproductive technologies, particularly for in vitro fertilization (IVF) protocols, as an alternative to traditional hormonal stimulation methods.
Hormone-Dependent Cancers: Some studies have suggested that kisspeptin-10 may have anti-metastatic properties in certain hormone-dependent cancers, such as breast and prostate cancer, although more research is needed in this area.
Side Effects
While kisspeptin-10 is generally well-tolerated, some potential side effects have been reported in animal studies and mammalian clinical trials. These include:
Transient hot flushes
Mild headache
Nausea
Fatigue
Injection site reactions (e.g., redness, swelling, or pain)
Summary
While kisspeptin-10 shows promise in various therapeutic applications, several challenges remain. These include optimizing delivery methods, understanding potential long-term effects, and elucidating its interactions with other neuroendocrine systems. Ongoing research aims to address these challenges and further explore the therapeutic potential of kisspeptin-10 in reproductive medicine and beyond.
In conclusion, kisspeptin-10 represents a significant area of interest in reproductive endocrinology and neuroendocrinology. Its central role in the HPG axis and potential therapeutic applications make it a valuable target for continued scientific investigation and clinical research.
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© 2025, Peptide Supplied™. All Rights Reserved.
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Company
All products on this site are intended for research and development purposes only and are not meant for human consumption of any kind. Neither the statements nor the products offered by this company are intended to diagnose, treat, cure, or prevent any disease.
© 2025, Peptide Supplied™. All Rights Reserved.