Product Usage: This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals. It is not approved for human or animal consumption. Misuse, misbranding, or mislabeling as a drug, food, or cosmetic is strictly prohibited. All information provided is for educational purposes only.
MOTS-C
£39.99
In stock
MOTS-c is a revolutionary mitochondrial-derived peptide that has been extensively researched for its potential health benefits. This peptide is a promising candidate for various therapeutic applications, including metabolic regulation, neuroprotection, and anti-aging effects. MOTS-c is a naturally occurring peptide that is encoded by the mitochondrial genome and has been shown to play a crucial role in cellular energy metabolism and homeostasis. Requires reconstitution before use.
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Size:
5 mg
Ships tomorrow morning if ordered by 2PM UTC
Free international delivery within 1-3 business days on orders over £250, with a tracking number provided.
Third party tested
FREE Bacteriostatic Water
For every £75 you spend, get 1 FREE bottle of Bacteriostatic Water to reconstitute your peptides.
MOTS-C
£39.99
In stock
Buy 3+ for £50 each and save 5%
Buy 5+ for £50 each and save 8%
Buy 10+ for £50 each and save 10%
Loading stock...
Size:
5 mg
Ships tomorrow morning if ordered by 2PM UTC
Free international delivery within 1-3 business days on orders over £250, with a tracking number provided.
Third party tested
FREE Bacteriostatic Water
For every £75 you spend, get 1 FREE bottle of Bacteriostatic Water to reconstitute your peptides.
MOTS-c is a revolutionary mitochondrial-derived peptide that has been extensively researched for its potential health benefits. This peptide is a promising candidate for various therapeutic applications, including metabolic regulation, neuroprotection, and anti-aging effects. MOTS-c is a naturally occurring peptide that is encoded by the mitochondrial genome and has been shown to play a crucial role in cellular energy metabolism and homeostasis. Requires reconstitution before use.
Product Usage: This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals. It is not approved for human or animal consumption. Misuse, misbranding, or mislabeling as a drug, food, or cosmetic is strictly prohibited. All information provided is for educational purposes only.
Characteristics
Molecular Formula
C225H348N60O68
CAS Number
2023788-19-2
Molar Mass
5047.61g/mol
Amino Acid
Sequence
His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Synonyms
LY3298176
Solubility
Water-soluble |
Organoleptic Profile
White to off-white powder
Composition
Lyophilized powder - requires reconstitution
How does MOTS-c work?
MOTS-c exerts its effects through multiple mechanisms of action. One of the primary ways MOTS-c functions is by regulating cellular energy metabolism. It has been shown to enhance insulin sensitivity, improve glucose uptake, and promote fatty acid oxidation in skeletal muscle cells. MOTS-c also activates the AMP-activated protein kinase (AMPK) pathway, which is a central regulator of cellular energy homeostasis. By activating AMPK, MOTS-c can stimulate glucose and fatty acid metabolism, leading to improved metabolic health. In addition to its metabolic effects, MOTS-c has demonstrated neuroprotective properties. Studies have shown that MOTS-c can protect against oxidative stress-induced damage in neuronal cells and improve cognitive function in animal models of Alzheimer's disease. MOTS-c has also been found to promote the expression of brain-derived neurotrophic factor (BDNF), which is essential for neuronal survival, growth, and plasticity. Furthermore, MOTS-c has been implicated in the regulation of aging processes. It has been shown to extend lifespan in animal models and improve various age-related parameters, such as muscle function and bone density. MOTS-c has also been found to modulate the expression of genes involved in longevity pathways, such as the sirtuin family of proteins.
Research
The potential benefits of MOTS-c are numerous and far-reaching. Some of the key benefits supported by research include:
Improved metabolic health MOTS-c has been shown to enhance insulin sensitivity, glucose uptake, and fatty acid oxidation, leading to better metabolic regulation and reduced risk of metabolic disorders such as type 2 diabetes and obesity.
Neuroprotection MOTS-c has demonstrated neuroprotective effects, including protection against oxidative stress-induced damage and improvement of cognitive function in animal models of neurodegenerative diseases.
Anti-aging effects MOTS-c has been found to extend lifespan in animal models and improve various age-related parameters, suggesting its potential as an anti-aging intervention.
Cardioprotection Studies have shown that MOTS-c can protect against ischemia-reperfusion injury in the heart and improve cardiac function in animal models of cardiovascular disease.
Bone health MOTS-c has been found to promote bone formation and prevent bone loss in animal models, indicating its potential for maintaining bone health and preventing osteoporosis.
Side Effects
To date, no significant side effects of MOTS-c have been reported in the available research studies. However, it is important to note that most of the studies have been conducted in animal models or in vitro cell cultures, and further research is needed to fully understand the safety profile of MOTS-c in mammals. As with any new therapeutic agent, caution should be exercised, and proper dosing and administration protocols should be followed.
No significant side effects reported in available research studies
Most studies conducted in animal models or in vitro cell cultures
Further research needed to understand safety profile in mammals
Caution should be exercised with any new therapeutic agent
Proper dosing and administration protocols should be followed
Summary
MOTS-c is a promising mitochondrial-derived peptide with a wide range of potential health benefits. Research has shown that MOTS-c can regulate cellular energy metabolism, provide neuroprotection, extend lifespan, protect against cardiovascular disease, and promote bone health. Its unique mechanism of action, which involves the activation of key metabolic pathways such as AMPK and the modulation of longevity-related genes, makes it an attractive candidate for various therapeutic applications. While the current evidence is primarily based on animal studies and in vitro experiments, the findings suggest that MOTS-c may have significant implications for human health. Further research is needed to fully elucidate the effects of MOTS-c in mammals and to develop safe and effective therapeutic strategies based on this innovative peptide.
Characteristics
Molecular Formula
C225H348N60O68
CAS Number
2023788-19-2
Molar Mass
5047.61g/mol
Amino Acid
Sequence
His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Synonyms
LY3298176
Solubility
Water-soluble |
Organoleptic Profile
White to off-white powder
Composition
Lyophilized powder - requires reconstitution
How does MOTS-c work?
MOTS-c exerts its effects through multiple mechanisms of action. One of the primary ways MOTS-c functions is by regulating cellular energy metabolism. It has been shown to enhance insulin sensitivity, improve glucose uptake, and promote fatty acid oxidation in skeletal muscle cells. MOTS-c also activates the AMP-activated protein kinase (AMPK) pathway, which is a central regulator of cellular energy homeostasis. By activating AMPK, MOTS-c can stimulate glucose and fatty acid metabolism, leading to improved metabolic health. In addition to its metabolic effects, MOTS-c has demonstrated neuroprotective properties. Studies have shown that MOTS-c can protect against oxidative stress-induced damage in neuronal cells and improve cognitive function in animal models of Alzheimer's disease. MOTS-c has also been found to promote the expression of brain-derived neurotrophic factor (BDNF), which is essential for neuronal survival, growth, and plasticity. Furthermore, MOTS-c has been implicated in the regulation of aging processes. It has been shown to extend lifespan in animal models and improve various age-related parameters, such as muscle function and bone density. MOTS-c has also been found to modulate the expression of genes involved in longevity pathways, such as the sirtuin family of proteins.
Research
The potential benefits of MOTS-c are numerous and far-reaching. Some of the key benefits supported by research include:
Improved metabolic health MOTS-c has been shown to enhance insulin sensitivity, glucose uptake, and fatty acid oxidation, leading to better metabolic regulation and reduced risk of metabolic disorders such as type 2 diabetes and obesity.
Neuroprotection MOTS-c has demonstrated neuroprotective effects, including protection against oxidative stress-induced damage and improvement of cognitive function in animal models of neurodegenerative diseases.
Anti-aging effects MOTS-c has been found to extend lifespan in animal models and improve various age-related parameters, suggesting its potential as an anti-aging intervention.
Cardioprotection Studies have shown that MOTS-c can protect against ischemia-reperfusion injury in the heart and improve cardiac function in animal models of cardiovascular disease.
Bone health MOTS-c has been found to promote bone formation and prevent bone loss in animal models, indicating its potential for maintaining bone health and preventing osteoporosis.
Side Effects
To date, no significant side effects of MOTS-c have been reported in the available research studies. However, it is important to note that most of the studies have been conducted in animal models or in vitro cell cultures, and further research is needed to fully understand the safety profile of MOTS-c in mammals. As with any new therapeutic agent, caution should be exercised, and proper dosing and administration protocols should be followed.
No significant side effects reported in available research studies
Most studies conducted in animal models or in vitro cell cultures
Further research needed to understand safety profile in mammals
Caution should be exercised with any new therapeutic agent
Proper dosing and administration protocols should be followed
Summary
MOTS-c is a promising mitochondrial-derived peptide with a wide range of potential health benefits. Research has shown that MOTS-c can regulate cellular energy metabolism, provide neuroprotection, extend lifespan, protect against cardiovascular disease, and promote bone health. Its unique mechanism of action, which involves the activation of key metabolic pathways such as AMPK and the modulation of longevity-related genes, makes it an attractive candidate for various therapeutic applications. While the current evidence is primarily based on animal studies and in vitro experiments, the findings suggest that MOTS-c may have significant implications for human health. Further research is needed to fully elucidate the effects of MOTS-c in mammals and to develop safe and effective therapeutic strategies based on this innovative peptide.
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All products on this site are intended for research and development purposes only and are not meant for human consumption of any kind. Neither the statements nor the products offered by this company are intended to diagnose, treat, cure, or prevent any disease.
© 2025, Peptide Supplied™. All Rights Reserved.
Subscribe to our newsletter
Receive weekly updates with the newest insights, trends, and tools, straight to your email.
PEPTIDE
SUPPLIED
Contact Us
Email:
support@peptidesupplied.com
Peptides
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Company
All products on this site are intended for research and development purposes only and are not meant for human consumption of any kind. Neither the statements nor the products offered by this company are intended to diagnose, treat, cure, or prevent any disease.
© 2025, Peptide Supplied™. All Rights Reserved.