Product Usage: This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals. It is not approved for human or animal consumption. Misuse, misbranding, or mislabeling as a drug, food, or cosmetic is strictly prohibited. All information provided is for educational purposes only.
TB-500
£119.99
In stock
TB-500, also known as Thymosin Beta-4 (Tβ4), is a naturally occurring peptide that has shown promise in promoting wound healing, reducing inflammation, and stimulating hair growth. TB-500 has been extensively studied for its potential therapeutic applications in various fields, including dermatology, ophthalmology, and regenerative medicine. Requires reconstitution before use.
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Size:
10 mg
Ships tomorrow morning if ordered by 2PM UTC
Free international delivery within 1-3 business days on orders over £250, with a tracking number provided.
Third party tested
FREE Bacteriostatic Water
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TB-500
£119.99
In stock
Buy 3+ for £50 each and save 5%
Buy 5+ for £50 each and save 8%
Buy 10+ for £50 each and save 10%
Loading stock...
Size:
10 mg
Ships tomorrow morning if ordered by 2PM UTC
Free international delivery within 1-3 business days on orders over £250, with a tracking number provided.
Third party tested
FREE Bacteriostatic Water
For every £75 you spend, get 1 FREE bottle of Bacteriostatic Water to reconstitute your peptides.
TB-500, also known as Thymosin Beta-4 (Tβ4), is a naturally occurring peptide that has shown promise in promoting wound healing, reducing inflammation, and stimulating hair growth. TB-500 has been extensively studied for its potential therapeutic applications in various fields, including dermatology, ophthalmology, and regenerative medicine. Requires reconstitution before use.
Product Usage: This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals. It is not approved for human or animal consumption. Misuse, misbranding, or mislabeling as a drug, food, or cosmetic is strictly prohibited. All information provided is for educational purposes only.
Characteristics
Molecular Formula
C225H348N60O68
CAS Number
2023788-19-2
Molar Mass
5047.61g/mol
Amino Acid
Sequence
His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Synonyms
LY3298176
Solubility
Water-soluble |
Organoleptic Profile
White to off-white powder
Composition
Lyophilized powder - requires reconstitution
How does TB-500 work?
TB-500 is a synthetic version of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid peptide conserved across species and expressed in various tissues. Research has shown that TB-500 interacts with actin, a protein crucial for cell migration and tissue remodeling. This interaction promotes actin polymerization, which is essential for angiogenesis and cell migration to injury sites. Studies have demonstrated that TB-500 modulates the expression of genes involved in inflammation, wound healing, and tissue regeneration. For instance, it has been found to upregulate matrix metalloproteinases (MMPs), enzymes key to extracellular matrix remodeling and wound healing.
Research
Research in mammalian models has revealed:
Wound healing: TB-500 has been shown to enhance keratinocyte and fibroblast migration, stimulate angiogenesis, and reduce inflammation, contributing to faster healing in various wound types.
Anti-inflammatory effects: Studies have demonstrated TB-500's ability to reduce pro-inflammatory cytokine production and increase anti-inflammatory cytokine levels in various inflammatory conditions.
Hair growth stimulation: Research using mammalian models has found that TB-500 can increase hair follicle size and promote the transition from telogen to anagen phase.
Neuroprotection: Studies have explored TB-500's potential to reduce neuroinflammation, oxidative stress, and apoptosis in models of neurological disorders.
Cardioprotection: In mammalian models of myocardial infarction, TB-500 has been shown to reduce infarct size, improve cardiac function, and promote angiogenesis.
While these findings are promising, it is important to note that TB-500 is currently a research tool, and its effects in mammals are still being studied.
Side Effects
Injection site reactions (pain, redness, swelling)
Headache
Nausea
Dizziness
Fatigue
Summary
TB-500, a synthetic version of the naturally occurring peptide Thymosin Beta-4, has shown remarkable potential in various research settings. The peptide has been extensively studied for its ability to promote wound healing, reduce inflammation, stimulate hair growth, provide neuroprotection, and offer cardioprotection. TB-500 exerts its effects through multiple mechanisms, including its interaction with actin, modulation of gene expression, and regulation of inflammatory pathways.
As a research tool, TB-500 offers a valuable opportunity to explore the complex mechanisms underlying wound healing, inflammation, and tissue regeneration. The insights gained from these studies may pave the way for the development of novel therapeutic strategies for a wide range of conditions, from skin wounds and hair loss disorders to neurodegenerative diseases and cardiovascular disorders.
Characteristics
Molecular Formula
C225H348N60O68
CAS Number
2023788-19-2
Molar Mass
5047.61g/mol
Amino Acid
Sequence
His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly
Synonyms
LY3298176
Solubility
Water-soluble |
Organoleptic Profile
White to off-white powder
Composition
Lyophilized powder - requires reconstitution
How does TB-500 work?
TB-500 is a synthetic version of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid peptide conserved across species and expressed in various tissues. Research has shown that TB-500 interacts with actin, a protein crucial for cell migration and tissue remodeling. This interaction promotes actin polymerization, which is essential for angiogenesis and cell migration to injury sites. Studies have demonstrated that TB-500 modulates the expression of genes involved in inflammation, wound healing, and tissue regeneration. For instance, it has been found to upregulate matrix metalloproteinases (MMPs), enzymes key to extracellular matrix remodeling and wound healing.
Research
Research in mammalian models has revealed:
Wound healing: TB-500 has been shown to enhance keratinocyte and fibroblast migration, stimulate angiogenesis, and reduce inflammation, contributing to faster healing in various wound types.
Anti-inflammatory effects: Studies have demonstrated TB-500's ability to reduce pro-inflammatory cytokine production and increase anti-inflammatory cytokine levels in various inflammatory conditions.
Hair growth stimulation: Research using mammalian models has found that TB-500 can increase hair follicle size and promote the transition from telogen to anagen phase.
Neuroprotection: Studies have explored TB-500's potential to reduce neuroinflammation, oxidative stress, and apoptosis in models of neurological disorders.
Cardioprotection: In mammalian models of myocardial infarction, TB-500 has been shown to reduce infarct size, improve cardiac function, and promote angiogenesis.
While these findings are promising, it is important to note that TB-500 is currently a research tool, and its effects in mammals are still being studied.
Side Effects
Injection site reactions (pain, redness, swelling)
Headache
Nausea
Dizziness
Fatigue
Summary
TB-500, a synthetic version of the naturally occurring peptide Thymosin Beta-4, has shown remarkable potential in various research settings. The peptide has been extensively studied for its ability to promote wound healing, reduce inflammation, stimulate hair growth, provide neuroprotection, and offer cardioprotection. TB-500 exerts its effects through multiple mechanisms, including its interaction with actin, modulation of gene expression, and regulation of inflammatory pathways.
As a research tool, TB-500 offers a valuable opportunity to explore the complex mechanisms underlying wound healing, inflammation, and tissue regeneration. The insights gained from these studies may pave the way for the development of novel therapeutic strategies for a wide range of conditions, from skin wounds and hair loss disorders to neurodegenerative diseases and cardiovascular disorders.
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All products on this site are intended for research and development purposes only and are not meant for human consumption of any kind. Neither the statements nor the products offered by this company are intended to diagnose, treat, cure, or prevent any disease.
© 2025, Peptide Supplied™. All Rights Reserved.
Subscribe to our newsletter
Receive weekly updates with the newest insights, trends, and tools, straight to your email.
PEPTIDE
SUPPLIED
Contact Us
Email:
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Company
All products on this site are intended for research and development purposes only and are not meant for human consumption of any kind. Neither the statements nor the products offered by this company are intended to diagnose, treat, cure, or prevent any disease.
© 2025, Peptide Supplied™. All Rights Reserved.